Dr Jays RETA™ (Retatrutide) Research Compound
Research-grade retatrutide compound for laboratory study of GIP/GLP-1/glucagon receptor pathways. Available in multiple research quantities from 5mg to 100mg. Swiss-sourced, batch-traceable, COA included with every order. Third-party verified purity ≥98%. Ships cold-chain from Jacksonville, FL. Research use only — not for human or veterinary consumption.
SKU FC2005-RETA · In stock
- Batch-verified Certificate of Analysis included
- Bacteriostatic water included free with every vial
- Same-day cold-chain dispatch from Jacksonville, FL
- Swiss-sourced, ≥98% HPLC-verified purity
Available in multiple research quantities from 5mg to 100mg
| Size | SKU | Price | Best for | Availability | Select |
|---|---|---|---|---|---|
| 5mg | FC2005-RETA | $64.00 | Triple-receptor pilots and titration work | In stock | Select 5mg |
| 10mg | FC2010-RETA | $118.00 | Short bench protocols and stability screening | In stock | Select 10mg |
| 15mg | FC2015-RETA | $147.00 | Multi-assay receptor signaling studies | In stock | Select 15mg |
| 30mg | FC2030-RETA | $220.00 | Stability-over-time and lyophilisate research | In stock | Select 30mg |
| 40mg | FC2040-RETA | $250.00 | Triple-pathway signaling models | In stock | Select 40mg |
| 60mg | FC2060-RETA | $340.00 | Tri-receptor activation studies, formulation work | In stock | Select 60mg |
| 80mg | FC2080-RETA | $269.50 | Programme-scale tri-agonist research | In stock | Select 80mg |
| 100mg | FC2100-RETA | $301.00 | Programme-scale research and analytical batches | In stock | Select 100mg |
What you receive
- Sealed, lyophilized vial in the selected research size
- Bacteriostatic water — appropriate size for reconstitution, included free
- Batch-verified Certificate of Analysis with HPLC chromatogram
- Secure cold-chain packaging with gel packs
Retatrutide For Sale – Research-Grade LY3437943 (99.8% Purity)
Retatrutide (development code LY3437943) is a triple GIP/GLP-1/glucagon receptor agonist peptide currently in Phase 3 clinical trials for metabolic research. Our research-grade Retatrutide is synthesized under cGMP conditions and verified by third-party HPLC analysis to ≥99.8% purity—exceeding industry standards for laboratory reference materials.
Your Research Order Includes:
- 1× Retatrutide Vial – 10mg lyophilized peptide (≥99.8% purity, HPLC verified)
- Bacteriostatic Water – 2mL sterile water for injection, 0.9% benzyl alcohol (preservative)
- Certificate of Analysis – Batch-specific COA with HPLC chromatogram and MS data
- Research Data Sheet – Handling protocols, solubility guidelines, storage parameters
- Secure Packaging – Insulated shipping container with gel packs (cold-chain maintained)
Research applications include receptor binding studies, stability analysis, and metabolic pathway investigation. Not for human consumption, veterinary use, or diagnostic procedures.
Why Researchers Choose Our Retatrutide
| Specification | Detail |
|---|---|
| Compound Name | Retatrutide |
| Development Code | LY3437943 |
| CAS Number | 2381089-83-2 |
| Sequence | Tyr-Aib-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-Aib-Trp-Leu-Tyr-Leu-Asp-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH₂ |
| Sequence (Single Letter) | YAEGTFSDY SIWLVLDGGP SSGAPPPPS-NH₂ |
| Molecular Formula | C₁₇₄H₂₉₈N₅₄O₅₉ |
| Molecular Weight | 3,911.66 g/mol |
| Purity | ≥99.8% (HPLC verified) |
| Form | Lyophilized (freeze-dried) powder |
| Appearance | White to off-white crystalline powder |
| Solubility | Soluble in aqueous buffer (pH 7-8), DMSO |
| Storage | -20°C (lyophilized), 2-8°C after reconstitution |
| Reconstitution | Bacteriostatic water (0.9% benzyl alcohol) included |
| Stability | Lyophilized: 24 months; Reconstituted: 30 days refrigerated |
| Testing Method | Reverse-phase HPLC, Mass Spectrometry (MALDI-TOF) |
| Source | Swiss pharmaceutical-grade synthesis (cGMP) |
| Packaging | Sealed 10mL research vial, crimp-sealed, nitrogen-purged |
Chemical Class: Triple agonist peptide (GIP/GLP-1/Glucagon receptor)
Mechanism: Activates glucose-dependent insulinotropic polypeptide (GIP), glucagon-like peptide-1 (GLP-1), and glucagon receptors
Research Applications: Metabolic pathway studies, receptor binding assays, stability analysis, formulation research
Molecular Structure & Properties
Retatrutide is a 39-amino acid linear peptide with C-terminal amidation. Key structural features:
- N-terminal modifications: Tyr-Aib (aminoisobutyric acid) substitution at position 2 enhances proteolytic stability
- Fatty acylation: C20 fatty diacid moiety attached via γ-Glu-2xOEG linker (not present in vial; this is the clinical formulation modification)
- Helical structure: Amphipathic α-helix configuration enables triple-receptor binding
Receptor Binding Profile (Research Data)
| Receptor | EC₅₀ (nM) | Efficacy |
|---|---|---|
| GLP-1R | 0.17 | Full agonist |
| GIPR | 0.08 | Full agonist |
| GCGR | 0.66 | Full agonist |
Source: Rosenstock et al., NEJM 2023; Phase 1 trial data
Stability & Handling Specifications
Lyophilized Powder
- Store at -20°C for maximum stability (24 months)
- Short-term: 2-8°C acceptable (6 months)
- Protect from light and moisture
- Allow vial to reach room temperature before opening (prevents condensation)
Reconstituted Solution
- Use provided bacteriostatic water (10mg vial: add 2mL for 5mg/mL concentration)
- Gently swirl; do not shake (prevents peptide aggregation)
- Store at 2-8°C, use within 30 days
- Do not freeze reconstituted solution
Clinical Research Context
Retatrutide (LY3437943) is being investigated in the SURMOUNT and TRIUMPH clinical trial programs:
- SURMOUNT-1 (Phase 3, obesity): 48-week data showing mean weight reduction of 24.2% at highest dose
- SURMOUNT-2 (Phase 3, obesity with T2D): Mean weight reduction 15.7% (10mg), 21.4% (15mg)
- SURMOUNT-3 (12-week intensive lifestyle intervention lead-in)
- TRIUMPH-3 (Phase 3, cardiovascular outcomes) — ongoing
Mechanism Research
The triple agonist profile produces synergistic metabolic effects through:
- Enhanced insulin secretion (GLP-1R + GIPR)
- Reduced glucagon secretion (GLP-1R mediated)
- Increased energy expenditure (GCGR mediated thermogenesis)
- Appetite regulation (central GLP-1R/GIPR signaling)
All clinical data cited for research context only. Product not approved for human use.
Last updated: July 31, 2026
Retatrutide Research Guide 2026
What is Retatrutide?
Retatrutide (LY3437943) is a synthetic triple receptor agonist that simultaneously engages the GIP, GLP-1, and glucagon receptors. That three-way profile is what distinguishes it from semaglutide, a single GLP-1 receptor agonist, and from tirzepatide, a dual GIP/GLP-1 agonist. In laboratory settings the added glucagon-receptor arm is the primary variable researchers isolate when comparing incretin-class reference materials.
Current Research Status (2026)
- • Phase 3 trials ongoing across the manufacturer's late-stage program (TRIUMPH / SURMOUNT-class studies)
- • Mechanism: coordinated GIP, GLP-1, and glucagon receptor activation
- • Research applications: metabolic function, energy regulation, and receptor-binding studies
Retatrutide vs. Tirzepatide vs. Semaglutide
| Feature | Retatrutide | Tirzepatide | Semaglutide |
|---|---|---|---|
| Receptor targets | Triple (GIP / GLP-1 / glucagon) | Dual (GIP / GLP-1) | Single (GLP-1) |
| Research code | LY3437943 | LY3298176 | NN9535 / semaglutide |
| Status | Phase 3 investigational | Approved (clinical use) | Approved (clinical use) |
| Half-life (reported) | ~6 days | ~5 days | ~7 days |
| Study focus | Metabolic + energy expenditure | Glycemic + body-weight endpoints | Glycemic + body-weight endpoints |
| Availability here | Research-use only material | Research-use only material | Research-use only material |
Pricing & Availability (2026)
| Vial size | Price | Typical use |
|---|---|---|
| 5 mg | $65.00 | Entry-level studies |
| 10 mg | $82.60 | Most popular |
| 15 mg | $140.00 | Mid-range protocols |
| 30 mg | $180.00 | Extended protocols |
| 40 mg | $235.00 | Multi-arm studies |
| 60 mg | $325.00 | Long research arcs |
| 80 mg | $385.00 | Programme-scale work |
| 100 mg | $430.00 | Bulk laboratory reference |
Prices current as of July 2026. Subject to raw material availability. Live pricing and stock for each vial size are shown in the buy box above.
About 5MG
Dr. Jays RETA 5MG — a research-grade triple agonist peptide
Dr. Jays RETA 5MG is a lab-made peptide. This makes it a valuable tool for researchers studying metabolism, energy use, and weight control. Scientists use Dr. Jays RETA 5MG in laboratory tests.
Preclinical and clinical studies, such as LY3437943 and TRIUMPH-3, show research applications. This allows researchers to observe peptides in research. These findings also open new directions for studying obesity and related metabolic conditions.
Researchers receive Dr. Jays RETA 5MG as a pure, lyophilized powder, ready for mixing with a lab-grade liquid before use. While dosing instructions are not provided, scientists can rely on its purity, accuracy, and consistency because each batch follows strict laboratory quality standards and testing procedures.
Dr. Jays RETA 5MG is for research use only and not for human consumption. Through this peptide, researchers study processes while achieving clear and repeatable results. Overall, it provides a reliable and efficient way to explore research in controlled research environments.
Choose your strength
Seven research-grade strengths
Every vial of DRJAYS RETA™ is lyophilized, batch-controlled, and individually sealed. Pick the strength that fits your study scope.
- VialViewing5MG
Entry / pilot studies
$65.00View → - Vial10MG
Short study windows
$100.00View → - Vial15MG
Mid-range study cycle
$140.00View → - Vial30MG
Multi-week research arc
$180.00View → - Vial40MG
Multi-week research arc
$235.00View → - Vial60MG
Long research arc
$325.00View → - Vial80MG
Long research arc
$385.00View → - Vial100MG
Full lab program
$430.00View →
Scientific workflow
From compound to study
- 01Research Compound
Defined peptide sequence
- 02Molecular Analysis
Identity & purity
- 03Laboratory Evaluation
Stability & form
- 04Data Collection
Batch records
- 05Research Applications
Investigator-led study
Product overview
Built for the bench
Lyophilized format
Researchers receive Dr. Jays Reta 5MG as a pure, lyophilized powder, ready for mixing with a lab-grade liquid before use. Freeze-dried for stable storage and reconstituted by the receiving laboratory under its own protocols.
Research-grade handling
Each batch follows strict laboratory quality standards and testing procedures. Manufactured with batch-level controls and laboratory packaging so scientists can rely on purity, accuracy, and consistency.
Laboratory applications
Designed for receptor interaction, stability, and analytical research conducted by qualified investigators.
Stability considerations
Store sealed at 2°C–8°C. Protect from heat and direct light. Follow your laboratory's SOPs.
Packaging standards
Each vial is individually sealed and dispatched in protective outer packaging suitable for research transit.
Independent verification
Independent laboratories confirm content and results so investigators can trust material integrity.
Why researchers choose us
Six pillars behind every vial
Research Grade Standards
Strict procedures from manufacturing through dispatch.
Premium Packaging
Sealed vials and protective outer packaging engineered for research transit.
Quality Focused Sourcing
Independent verification supports every batch we ship.
Educational Resources
Peptide University™, the Knowledge Hub, and dedicated guides.
Knowledge Hub Access
Browse applied articles and structured learning paths.
Peptide Finder™ Integration
Find compounds by research area, mechanism, or class.
Specifications
Product specifications
| Specification | Detail |
|---|---|
| Product Name | DRJAYS RETA™ |
| Form | Lyophilized (freeze-dried) powder |
| Appearance | White to off-white powder |
| Storage | Refrigerated, 2°C – 8°C |
| Container | Sealed research vial with crimp closure |
| Category | Research peptide — triple agonist |
| Receptor Targets | GLP-1, GIP and Glucagon receptors (study context) |
| Use | Laboratory research and analytical applications only |
Certificate of Analysis (COA) – Batch Verified
Every Retatrutide vial ships with a batch-specific Certificate of Analysis documenting:
- HPLC purity analysis (≥99.8%)
- Molecular weight confirmation
- Peptide identity verification (MS data)
- Appearance and solubility standards
- Stability testing results
COAs are available for download immediately after shipment. Batch records retained for 5 years per research material standards.
Research applications
Where DRJAYS RETA™ fits in the lab
For investigator-led laboratory study only. No medical claims, no dosing, no human or veterinary use.
Metabolism & energy research
Investigate how Dr. Jays Reta 5MG influences metabolism, energy use, and weight control in laboratory models.
Receptor interaction
Study binding behaviour across GLP-1, GIP and Glucagon receptor targets in vitro.
Clinical study reference
Preclinical and clinical studies such as LY3437943 and TRIUMPH-3 demonstrate research applications, allowing investigators to observe peptides in controlled research settings.
Laboratory analysis
Characterize peptide identity, purity, and behaviour using analytical methods.
Stability evaluation
Evaluate lyophilizate stability under controlled storage and reconstitution conditions.
Analytical testing
Support HPLC, mass spectrometry and other quality-control evaluations.
Compare strengths
All seven strengths, side by side
| Strength | Research Quantity | Vial Size | Best For | |
|---|---|---|---|---|
| 5MG | Entry / pilot studies | Single research vial | Triple-receptor pilots and titration work | View → |
| 10MG | Short study windows | Single research vial | Short bench protocols and stability screening | View → |
| 15MG | Mid-range study cycle | Single research vial | Multi-assay receptor signaling studies | View → |
| 30MG | Multi-week research arc | Single research vial | Stability-over-time and lyophilisate research | View → |
| 40MG | Multi-week research arc | Single high-capacity vial | Triple-pathway signaling models | View → |
| 60MG | Long research arc | Single high-capacity vial | Tri-receptor activation studies, formulation work | View → |
| 80MG | Long research arc | Single high-capacity vial | Programme-scale tri-agonist research | View → |
| 100MG | Full lab program | Single high-capacity vial | Programme-scale research and analytical batches | View → |
Knowledge hub
Keep learning
Trust
Why labs return to Dr Jays
- Quality Focused
- Research Oriented
- Educational Resources
- Responsive Support
- Secure Checkout
- Fast Shipping
Secure shipping
Vials ship in protective insulated packaging suitable for research peptide transit, with cold-chain considerations where appropriate. Track every step from dispatch to delivery.
Talk to our team →Retatrutide Research FAQ
Frequently Researched Together
About Dr Jays Peptides
Content reviewed for scientific accuracy by our research team.
Dr Jays Peptides is a veteran-owned research material supplier specializing in high-purity peptides for laboratory applications. Founded by Dr. Jay, a former U.S. Army 160th SOAR Special Operations Combat Medic, we source directly from Swiss pharmaceutical-grade manufacturers and verify every batch through independent HPLC analysis.
Our materials support researchers in:
- Endocrinology and metabolic studies
- Pharmaceutical development
- Academic laboratory research
All products are for research use only. We do not provide dosing guidance or therapeutic recommendations.
Learn more about Dr Jays Peptides →Research notice
DRJAYS RETA™ is supplied strictly for laboratory research and development purposes. It is not for human consumption, veterinary use, therapeutic use, diagnostic procedures or clinical applications. By purchasing, the buyer acknowledges responsibility for compliance with all applicable laws, regulations and laboratory standards. We do not provide dosing guidance of any kind.