Hormones · Dec 19, 2024
Kisspeptin: Upstream of the Entire HPG Axis
Summary
Kisspeptin is the upstream regulator of GnRH and the master switch for puberty and reproductive function. Synthetic analogs are an active research area.
Why It Matters
Most HPG-axis research peptides act downstream. Kisspeptin sits above gonadorelin and is increasingly discussed in fertility and libido research.
Key Findings
- Kisspeptin neurons act as the gatekeeper of GnRH pulses.
- Synthetic peptides studied in fertility and amenorrhea research.
- Discussed in libido-research contexts alongside PT-141.