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hCG

Also known as: Human Chorionic Gonadotropin
Sexual Function & HormonesBest known for: LH-mimicking fertility researchPopularity:
People searching for:
  • what is HCG
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Definition
hCG(Human Chorionic Gonadotropin)· Sexual Function & Hormones
HCG is a hormone that acts like LH. It walks up to LH receptors on the testes or ovaries and tells them to keep producing sex hormones — even when the brain has stopped sending its normal signal.

What is it?

HCG (Human Chorionic Gonadotropin) is a glycoprotein hormone naturally produced by the placenta during pregnancy. Structurally it closely mimics luteinizing hormone (LH) and binds the same LH receptor. It has long-standing approved clinical uses in fertility and testicular stimulation.

In plain English

HCG is a hormone that acts like LH. It walks up to LH receptors on the testes or ovaries and tells them to keep producing sex hormones — even when the brain has stopped sending its normal signal.

How it works

Binds LH receptors on Leydig cells in the testes (or theca cells in ovaries), driving testosterone production and supporting spermatogenesis indirectly. Its long half-life means dosing is much less frequent than Gonadorelin.

What researchers study

  • Hypogonadism research
  • Fertility and ovulation induction
  • Testicular preservation during androgen suppression studies
  • Comparison with Gonadorelin and Kisspeptin
  • Cryptorchidism research

What the internet talks about

HCG is the long-standing reference in TRT-adjacent communities and post-cycle research discussions. Threads compare it head-to-head with Gonadorelin on cost, half-life, and receptor desensitization risk.

Bro-science translation

The LH look-alike for testicular preservation.

Commonly compared to

Common stack discussions

Combined with exogenous testosterone protocols in TRT research. Often compared with Gonadorelin, Clomiphene, and Enclomiphene in fertility-preservation discussions.

Related peptides

Related categories

Frequently asked questions

Quick summary

HCG is an LH-mimicking hormone studied for testicular and ovarian stimulation, fertility, and testicular preservation. Sold for laboratory research only.

For laboratory and educational reference only. Not medical advice or a recommendation for human use.
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