Hormones · Sep 2, 2024
Tesamorelin: GHRH Analog With FDA Indication
Summary
Tesamorelin is the only FDA-approved GHRH analog, indicated for HIV-associated lipodystrophy, with extensive truncal-fat reduction research.
Why It Matters
Tesamorelin is the GH-axis peptide with the largest published clinical data set. It anchors a lot of GHRH-analog comparisons.
Key Findings
- Phase 3 trials showed meaningful reduction in visceral adipose tissue.
- IGF-1 elevations consistent with GHRH-axis activation.
- Clinical use confined to the FDA-approved indication.