Hormones · Aug 26, 2024
CJC-1295 vs Sermorelin: Why Half-Life Changes Everything
Summary
Both are GHRH analogs but sermorelin's half-life is minutes while CJC-1295 with DAC is days. That single difference changes the entire research-use profile.
Why It Matters
Half-life choice drives whether you're studying a GH 'pulse' or a steady state — which fundamentally changes what biology you're testing.
Key Findings
- Sermorelin: short pulse, more physiologic.
- CJC-1295 (no DAC): extended pulse over several hours.
- CJC-1295 with DAC: multi-day steady-state IGF-1 elevation.