hCG vs HMG
LH-like activity vs combined FSH/LH activity.
| Attribute | hCG Human Chorionic Gonadotropin | HMG Human Menopausal Gonadotropin, menotropin |
|---|---|---|
| Category | Sexual Function & Hormones | Sexual Function & Hormones |
| Best known for | LH-mimicking fertility research | FSH/LH research and fertility protocols |
| In plain English | hCG fakes out the testes into thinking the brain is sending an LH signal — keeping them producing testosterone during research protocols. | HCG mimics LH only; HMG provides both LH-like and FSH activity, which is important for sperm and egg development. |
| How it works | Binds the LH receptor on Leydig cells, stimulating testosterone production. | Provides exogenous FSH (drives spermatogenesis and follicle development) plus LH (drives testosterone and ovulation). |
| Researchers study | Fertility, hypogonadism, and post-cycle hormone restoration. | Fertility, hypogonadism, and post-cycle restart protocols. |
| Internet discussion | Standard PCT discussion topic. | Discussed in fertility-recovery and TRT restart research circles. |
hCG
LH-mimicking fertility research
hCG fakes out the testes into thinking the brain is sending an LH signal — keeping them producing testosterone during research protocols.
Binds the LH receptor on Leydig cells, stimulating testosterone production.
Fertility, hypogonadism, and post-cycle hormone restoration.
Standard PCT discussion topic.
hCG mimics LH at the testes and is heavily discussed in fertility and post-cycle protocols.
HMG
FSH/LH research and fertility protocols
HCG mimics LH only; HMG provides both LH-like and FSH activity, which is important for sperm and egg development.
Provides exogenous FSH (drives spermatogenesis and follicle development) plus LH (drives testosterone and ovulation).
Fertility, hypogonadism, and post-cycle restart protocols.
Discussed in fertility-recovery and TRT restart research circles.
HMG is a purified FSH/LH gonadotropin researched for fertility and full gonadal restart protocols.