MOTS-c

MOTS-c is a mitochondrial-derived peptide that owners most often ask about in relation to energy, metabolic health, and healthy ageing.

MOTS-c is a small peptide encoded within mitochondrial DNA and is involved in cellular metabolism and energy regulation. Owners typically ask our veterinary team about MOTS-c for older animals — a dog slowing down, a horse that seems to lack its usual spark, a cat carrying more weight than it should. The interest owners describe is in comfortable, healthy ageing rather than in reversing anything. Slowing down in an older animal is frequently a sign of pain, endocrine change, or organ disease, all of which are treatable and all of which need to be identified first. Our supervising veterinarian rules those out before considering a peptide protocol, and sets any protocol individually. MOTS-c is not approved by the FDA for use in animals and does not replace veterinary care.

04What Owners Ask About

What owners ask our veterinary team about MOTS-c

Owners in our program commonly bring up MOTS-c in connection with:

General wellness support
Owner questions we hear often
Species-specific considerations
How our veterinary team evaluates fit

“This is a commonly discussed compound in conversations with our veterinary team. Below are the areas owners most often ask about.”

General information only, shared to help you prepare for a conversation with our veterinary team. It is not a treatment plan, dosing, or a guarantee of any outcome — your animal's plan is set by our supervising veterinarian.

§Dosage Chart

MOTS-c — your animal dosing reference

Awaiting veterinary sign-off. These figures are finalised by our supervising veterinarian for your individual animal. Nothing here should be acted on until your veterinary team has reviewed your pet's species, weight, age, and health history.

MOTS-c dosing reference for your animal, populated and approved by the supervising veterinarian.
Weight / stage	Amount	Frequency	Duration	Vet notes
Small animal	[VET-APPROVED VALUE]	[VET-APPROVED VALUE]	[VET-APPROVED VALUE]	[VET-APPROVED VALUE]
Medium animal	[VET-APPROVED VALUE]	[VET-APPROVED VALUE]	[VET-APPROVED VALUE]	[VET-APPROVED VALUE]
Large animal	[VET-APPROVED VALUE]	[VET-APPROVED VALUE]	[VET-APPROVED VALUE]	[VET-APPROVED VALUE]

Every protocol in our pet peptide program is set under the guidance of our supervising veterinarian. Contact our veterinary team to have a plan reviewed for your animal.

Vet-supervised program

MOTS-c is offered through our vet-supervised pet and animal peptide program. Every plan — including whether MOTS-c is appropriate for your animal — is set by our supervising veterinarian after reviewing your animal's history. Browse our program →

Veterinarian-Supervised Program

Every peptide protocol in this section is set and overseen by our supervising veterinarian. Nothing on these pages is a diagnosis, a prescription, or a substitute for examining your animal — dosing is determined individually after veterinary review of your pet's species, weight, age, medications and health history. Peptides are used alongside, never instead of, care from a licensed veterinarian. These products are not approved by the FDA for use in animals. If your animal is unwell, injured, or showing new symptoms, contact a veterinarian first.