ACE-031 vs Follistatin
Activin receptor decoy vs myostatin-binding protein.
| Attribute | ACE-031 Activin receptor type IIB (soluble) | Follistatin FST-344 |
|---|---|---|
| Category | Muscle Growth & Performance | Muscle Growth & Performance |
| Best known for | Myostatin pathway inhibition research | Myostatin inhibition research |
| In plain English | It acts like a sponge that soaks up the signals telling your body to stop building muscle. | Myostatin is the brake on muscle growth. Follistatin is researched as the brake-release mechanism. |
| How it works | Binds circulating myostatin, activin A, and related TGF-β ligands before they can activate ActRIIB on muscle cells. | Binds and neutralizes myostatin, activin, and related TGF-β family members that limit muscle growth. |
| Researchers study | Muscular dystrophy, sarcopenia, and lean-mass research models. | Muscle hypertrophy, muscular dystrophy, and aging-related sarcopenia. |
| Internet discussion | Discussed alongside follistatin and YK-11 in muscle-growth research circles. | Hyped in bodybuilding research circles. |
ACE-031
Myostatin pathway inhibition research
It acts like a sponge that soaks up the signals telling your body to stop building muscle.
Binds circulating myostatin, activin A, and related TGF-β ligands before they can activate ActRIIB on muscle cells.
Muscular dystrophy, sarcopenia, and lean-mass research models.
Discussed alongside follistatin and YK-11 in muscle-growth research circles.
ACE-031 is a soluble ActRIIB decoy researched as a myostatin/activin trap to support muscle growth.
Follistatin
Myostatin inhibition research
Myostatin is the brake on muscle growth. Follistatin is researched as the brake-release mechanism.
Binds and neutralizes myostatin, activin, and related TGF-β family members that limit muscle growth.
Muscle hypertrophy, muscular dystrophy, and aging-related sarcopenia.
Hyped in bodybuilding research circles.
Follistatin is a glycoprotein researched for myostatin inhibition and muscle hypertrophy.