Hexarelin
- •what is Hexarelin
- •Hexarelin GH release
- •Hexarelin vs Ipamorelin
- •Hexarelin cardiac research
- •Hexarelin cortisol prolactin
- Hexarelin(Hexapeptide GH secretagogue)· Muscle Growth & Performance
- Hexarelin is the heavy hitter of the older GHRP family. It pushes the pituitary to release a strong GH pulse and also appears in heart-research discussions because of its cardiac receptor binding.
What is it?
Hexarelin is a synthetic six-amino-acid growth hormone-releasing peptide (GHRP) and ghrelin receptor agonist. It is one of the most potent GH-releasing peptides studied, and is notable for additional action at the cardiac CD36 receptor.
In plain English
Hexarelin is the heavy hitter of the older GHRP family. It pushes the pituitary to release a strong GH pulse and also appears in heart-research discussions because of its cardiac receptor binding.
How it works
Activates GHS-R1a (ghrelin) receptors on the pituitary to release growth hormone, and binds CD36 on cardiac tissue — the basis for cardioprotection research.
What researchers study
- •Pituitary GH release
- •Cardiac CD36 receptor research
- •Cardioprotection in ischemia models
- •Comparison with GHRP-2, GHRP-6, and Ipamorelin
- •Receptor desensitization studies
What the internet talks about
Discussed as the most potent GHRP, but also the one most likely to raise cortisol and prolactin compared to Ipamorelin. Community protocols typically cycle it.
Bro-science translation
“The heaviest hitter of the old-school GHRPs.”
Commonly compared to
Common stack discussions
Sometimes paired with a GHRH analog like CJC-1295 No DAC for synergistic GH pulses. Often replaced by Ipamorelin for a cleaner side-effect profile.
Related peptides
Related categories
Frequently asked questions
Quick summary
Hexarelin is a potent GHRP and ghrelin receptor agonist studied for GH release and cardiac CD36 research. Sold for laboratory research only.