Selank vs Semax
| Attribute | Selank Tuftsin analog | Semax ACTH(4-10) analog |
|---|---|---|
| Category | Brain & Cognitive Support | Brain & Cognitive Support |
| Best known for | Anxiolytic without sedation research | Cognitive enhancement research |
| In plain English | Selank is the chill peptide. Researchers study how it provides anti-anxiety effects without the sedation or dependence of benzodiazepines. | Semax is the focus peptide. Researchers study how it boosts BDNF and NGF — the brain's growth and repair factors. |
| How it works | Modulates GABA, serotonin, and BDNF; inhibits enkephalinase to increase enkephalin activity. | Upregulates BDNF and NGF expression, modulates dopamine and serotonin, and inhibits enkephalin breakdown. |
| Researchers study | Generalized anxiety, stress response, and immune modulation. | Cognitive function, ischemic stroke recovery, ADHD, and neuroprotection. |
| Internet discussion | The anti-anxiety peptide of choice on nootropic forums. | Stacked with Selank as the canonical Russian nootropic combo. |
Selank
Anxiolytic without sedation research
Selank is the chill peptide. Researchers study how it provides anti-anxiety effects without the sedation or dependence of benzodiazepines.
Modulates GABA, serotonin, and BDNF; inhibits enkephalinase to increase enkephalin activity.
Generalized anxiety, stress response, and immune modulation.
The anti-anxiety peptide of choice on nootropic forums.
Selank is an anxiolytic nootropic peptide researched for stress reduction without sedation.
Semax
Cognitive enhancement research
Semax is the focus peptide. Researchers study how it boosts BDNF and NGF — the brain's growth and repair factors.
Upregulates BDNF and NGF expression, modulates dopamine and serotonin, and inhibits enkephalin breakdown.
Cognitive function, ischemic stroke recovery, ADHD, and neuroprotection.
Stacked with Selank as the canonical Russian nootropic combo.
Semax is a nootropic peptide researched for BDNF/NGF upregulation and cognitive support.