Humanin vs SS-31
Cytoprotective peptide vs mitochondrial-targeted peptide.
| Attribute | Humanin Mitochondrial peptide | SS-31 Elamipretide |
|---|---|---|
| Category | Mitochondrial Health & Energy | Mitochondrial Health & Energy |
| Best known for | Neuroprotection and apoptosis research | Mitochondrial cardiolipin research |
| In plain English | Humanin is the survival peptide. It tells cells to live longer and resist stress, with strong neuroprotection signals in research. | SS-31 protects the mitochondria's energy-producing surface by stabilizing cardiolipin, the lipid that makes ATP production efficient. |
| How it works | Inhibits apoptosis (programmed cell death), reduces oxidative stress, and modulates inflammatory pathways. | Binds cardiolipin in the inner mitochondrial membrane, preserving electron transport chain efficiency and reducing reactive oxygen species. |
| Researchers study | Alzheimer's, atherosclerosis, diabetes, and longevity. | Heart failure, mitochondrial diseases, and age-related mitochondrial decline. |
| Internet discussion | Discussed in longevity and Alzheimer's research circles. | Discussed in longevity and athletic performance circles. |
Humanin
Neuroprotection and apoptosis research
Humanin is the survival peptide. It tells cells to live longer and resist stress, with strong neuroprotection signals in research.
Inhibits apoptosis (programmed cell death), reduces oxidative stress, and modulates inflammatory pathways.
Alzheimer's, atherosclerosis, diabetes, and longevity.
Discussed in longevity and Alzheimer's research circles.
Humanin is a mitochondrial-encoded peptide with strong neuroprotection and longevity research signals.
SS-31
Mitochondrial cardiolipin research
SS-31 protects the mitochondria's energy-producing surface by stabilizing cardiolipin, the lipid that makes ATP production efficient.
Binds cardiolipin in the inner mitochondrial membrane, preserving electron transport chain efficiency and reducing reactive oxygen species.
Heart failure, mitochondrial diseases, and age-related mitochondrial decline.
Discussed in longevity and athletic performance circles.
SS-31 is a mitochondria-targeted peptide that stabilizes cardiolipin in the inner mitochondrial membrane.