MOTS-c Dosage Guide & Research Calculator
This MOTS-c dosage guide pulls together reconstitution math, an embedded concentration calculator, and dose ranges for the mitochondrial-derived peptide MOTS-c reported in published preclinical research. All figures below summarize parameters reported in published preclinical or in-vitro research. They are provided for reference only and are not instructions for human or veterinary administration.
For laboratory and research use only. Not for human or veterinary use. The information below summarizes dosing parameters reported in published research and is provided for reference only — not as guidance for administration.
MOTS-c reconstitution math & mots-c dosage calculator
Reconstituting a lyophilized peptide gives a solution with a known concentration. The formula is simple:
Worked example: Adding 2 mL of bacteriostatic water to a 10 mg vial of MOTS-c yields 5,000 mcg/mL. 0.20 mL (20 units on a U-100 insulin syringe) of that solution contains 1,000 mcg (1 mg) of peptide.
Enter your values
The total mass of lyophilized powder listed on the vial label.
The volume of bacteriostatic water added to the vial.
The amount, in micrograms, to model in your concentration math (1 mg = 1,000 mcg).
Display volume in U-100 syringe units or plain mL.
Based on your inputs
This tool performs unit conversion and concentration math for research planning. It is not medical advice, not a dose recommendation, and not intended for human or veterinary use.
MOTS-c doses reported in published preclinical research
The figures below summarize MOTS-c doses that appear in published animal-model or in-vitro studies. They describe what researchers have used in laboratory settings — they are not human administration protocols and are not dose recommendations.
| Research context | Dose reported | Notes |
|---|---|---|
| Mouse model, intraperitoneal | 0.5 mg/kg/day | Commonly cited dose in published metabolic-research studies. |
| Mouse model, intraperitoneal | 5 mg/kg/day | Higher dose used in some published animal-model work. |
| In-vitro cell-culture assays | 1–10 µM | Concentrations referenced in published cell-culture studies. |
All values are research-context references compiled from published preclinical and in-vitro literature. MOTS-c is supplied for laboratory and research use only.
Continue your MOTS-c research
MOTS-c research dosage — frequently asked questions
How is MOTS-c reconstituted for research?+
Lyophilized MOTS-c is dissolved in bacteriostatic water. Concentration is calculated as (vial mg × 1000) ÷ diluent mL, giving mcg per mL.
What concentration does 10 mg MOTS-c in 2 mL give?+
10 mg in 2 mL of bacteriostatic water yields a 5,000 mcg/mL solution. 0.20 mL (20 units on a U-100 insulin syringe) contains 1,000 mcg (1 mg).
What MOTS-c doses are reported in published research?+
Published mouse-model studies most commonly report intraperitoneal doses of 0.5 mg/kg/day, with some studies using 5 mg/kg/day. In-vitro work generally references 1–10 µM.
Is this MOTS-c dosage guide for human use?+
No. MOTS-c is supplied for laboratory and research use only. The figures above describe parameters reported in published preclinical research and are not human administration instructions.
For laboratory and research use only. Not for human or veterinary use. The information below summarizes dosing parameters reported in published research and is provided for reference only — not as guidance for administration.